SULPHITES INTOLERANCE TO GENETIC TESTING

FOOD PRESERVATIVE

Sulfites are substances used since ancient times as a preservative. The Romans and the Egyptians employed sulfur dioxide by bacteria to clean up the fermenting vats where the vino.Tuttavia their use has become impressive only in the last century in conjunction with the new dietary requirements dictated by the development of the industrial system. Sulphites and derivatives are now used in large quantities in many foods in order to maintain their natural color and prevent the growth of microorganisms , get whitening where necessary, and even in the production of cellophane for packaged foods ; still to prevent rusting and fouling of boilers and are also used in medicines to prolong the therapeutic activity. They can be important source of sulphites: wine and spirits , bakery products such as bread , cookies , crackers , dried fruit , jams , jellies , syrups , fruit juices , fish , shellfish , molluscs , hot dogs , sausages , preserving species in alcohol , potatoes and derived products such as frozen chips , puree , chips , canned tomato , the candy , the packaged snacks , certain drugs.

WARNING LABELS ON THE INITIALS OF FOOD: E220 – E221 – E222 – E223 – E224 – E225 – E226 – E227 INDICATE THE PRESENCE OF OR CONSEQUENTIAL SULPHITES in the food.

INTOLERANCE BY SULPHITES

In healthy individuals , at the doses commonly used in the food industry , sulfur dioxide is considered to be a safe additive ; it is in fact also a natural compound produced by the body during the metabolism of certain amino acids and easily inactivated by detoxification systems endogenous. Despite this assurance the use of sulfur dioxide and sulphites can cause problems , sometimes serious , people prepared. The contact of sulphites food with gastric acidity generates a certain amount of sulfur dioxide , which represents one of the most effective in inducing gas attacks of bronchospasm in susceptible. Are particularly at risk of being subjected to this kind of reaction even people allergic to aspirin. In susceptible individuals , even small quantities , can trigger serious consequences; unfortunately it is very difficult to determine how many sulfites ingest or inhale; by law it is not mandatory to indicate their presence if the quantity is less than 10 mg / kg or lt. All this makes it essential prior knowledge of the tolerability of these preservatives or less.

HEALTH CONSEQUENCES

The damage caused by sulphites can: Cause allergic reactions or allergies with respiratory manifestations: rhinitis , hives , dysentery , asthma. Cause alterations in vitamin: sulfur dioxide and sulphites destroy thiamine and cyanocobalamin two vitamins are very important.. Overloading the detoxification system causing headaches. Interacting with cortisone

THE GENETIC TEST FOR INTOLERANCE TO SULPHITES

The genetic test is easy to perform , painless and non-invasive and provides a simple saliva collection. Are analyzed 4 gene mutations SUOX Sulfite Oxidase ( Q364X , S370S , S370Y , TAGA) and 2 in the CBS gene ( C699T , T1080C) involved in the detoxification of sulfites in the body. These polymorphisms , causing major deficiencies including that of vitamin B12, and an imbalance in the metabolism of homocysteine ​​blood , are also associated with a reduced risk of developing coronary heart disease. In the case of CBS SUOX and altered it is useful to avoid as well as foods that contain sulfites also foods rich in sulfur , some supplements , with caution and monitor certain drugs used as antihypertensive , antibiotics or chelating.  

THE Poterium spinosum and berberine: INSULIN PLANT

of VLADIMIRO PIGEONS

The Poterium spinosum, also known as Pimpinella spinosa (or as a plug ourselves in Tuscany) is a perennial shrub belonging to the family Rosaceae higher among 30 e i 60 cm of Middle-Eastern origin (Lebanon in particular) traditionally used in the geographical region for the prevention of diabetes and the treatment of disorders related to blood glucose. It grows mainly in Eastern Southern, in Greece, in Dalmatia, in Cyprus, Crete, Syria, Libya and Tunisia, but also in Italy in arid regions, such as some areas of Sardinia and Sicily. Historically there have always been the Bedouins to use as antidiabetic knowing the virtues hypoglycemic. Among these populations fact has been observed, as has often happened in the past for other great discoveries (omega 3 and heart attack for the Eskimo population, curry and Alzheimer's disease for the Indians, etc.…etc ...) that the Berber people who made great use, while feeding with a diet rich in carbohydrates and sugars, had very low incidence of diabetic diseases. The Bedouins fact are still usual bake the roots of this plant for long then sip during the day. In this way are able to maintain a low level of sugar in the blood while avoiding the well-known “blood sugar spikes” in the course of the day. In Italy it is still little known despite the latest research have now made clear what the operation of its main active: berberine. The first physician to use in our country was the dr. Luigi Oreste Speciani, who left a great legacy in the world of natural medicine (particularly with regard to his studies on the so-called “integrated man”, which has highlighted the report and the interference between the environment and humans and whose work today is a mainstay of Psychosomatic). It was he who obtained the first important results through the use of Poterium spinosum. Berberine is found not only in Poterium spinosum, but also in other plants, one of which is the Hydrastis canadensis, a plant used in herbal medicine for urinary tract infections. In 2010 was issued a warning about its use for a suspected risk of venous thrombosis, but there has not been a result of this news and today is normally marketed in various formulations. Its action is synergistic with silymarin, the active ingredient in milk thistle, a native plant very active in the prevention of hepatic steatosis and liver poisoning. It 'has been observed that in case of metabolic syndrome (that is when high blood pressure, high cholesterol and high sugar combine) His power increases when combined with milk thistle. Recent research on it have shown that it is able to reduce triglycerides, the risk of atherosclerosis and lower systemic inflammation, real target of global research at this time. However, it is possible that it is not the only berberine to have this hypoglycemic action, but rather a pool of substances contained in it. A German chemist Aiman ​​Kuzbari had collected a lot of evidence on possible actions and mechanisms of operation of the plant, but unfortunately his notes were lost after his death. He believed that they had more than one active principles responsible for the hypoglycaemic action of the plant, and that among them there was one that can very easily the islands of Langerhans, damaged cells in diabetes. In addition to these functions, the Poterium spinosum was used is known for its peripheral vasodilator action and corononarica, antihypertensive and antiarrhythmic, proving therefore very flexible for the protection of health in old age, but especially by the numerous damages that the diabetic disease produces the cardiovascular apparatus. It is a plant of which have never been observed side effects, which in the form of decoction can be used at a dosage of 20 grams per liter of water, but which can also be employed in the form of mother tincture.

INTOLERANCE TO CAFFEINE

A cup of coffee is a habit that many people can not do without. But is it really healthy for all? We start from the principle that caffeine is an alkaloid with numerous effects on the body: its chemical conformation makes it suitable to interact with specific receptors that regulate the function of the cardiovascular system , endocrine and nervous favoring the release of two important hormones adrenaline and noradrenaline , facilitating the increase in the body's metabolism , heart rate , blood pressure and respirations. Recent studies have expanded the knowledge on the interactions of caffeine, highlighting additional roles.

CAFFEINE AND HEALTH

An important recent study published in the Journal of the American Medical Associaton monitored 4000 persons referred to in 2000 recovering from myocardial infarction. Taking into account all the other factors has highlighted how people in poor metabolisers of caffeine were associated with a high risk of heart attack increases in proportion to the dose. “The risk of heart attack increases by 36% in poor metabolizers and you get up to 64% for high consumers of caffeine. The risk doubles if the age is less than 59 years and less than four times if 50.Chi instead presents the version of the gene associated with rapid metabolism of caffeine is protected from the risk of heart attack. Other studies correlate instead caffeine with fertility and pregnancy. These studies have shown that women with the gene encoding the slow metabolism of caffeine have a higher risk of abortions and reduce their fertility while those in fast metabolization not run these risks consuming the same amount of coffee.

CAFFEINE HIDDEN

Contrary to popular belief a long coffee , although it is less dense , contains more caffeine than normal, and even more than that restricted. We find the caffeine in coffee than in other beverages ( chocolate , tea , energy drinks , Coca Cola etc.…) now also increasingly being used in diet bars , herbal products , anti-cellulite cosmetics , and other specialties freely available. The data are average caffeine content : for a cup of tea or a can about 20-30 mg , a chocolate 10 mg , a can of Coca Cola 40 mg and an energy drink 80 mg.

THE GENETIC TEST OF CAFFEINE

The test is a simple and accurate genetic test painless and non-invasive ( saliva sample ) to check whether a person has a fast or slow metabolism of caffeine. Caffeine is metabolized in the body by the enzyme cytochrome p450 1A2. Each person has two copies of the gene CYP1A2. There are two gene variants that affect the metabolism of caffeine. Individuals who possess two pairs CYP1A2 * 1A allele are fast metabolizers of caffeine , while subjects presenting even a single allele CYP1A2 * 1F are poor metabolizers. Individuals who slowly metabolize caffeine should be monitored daily dose , if you consume it in a major way ( 2/3 cups a day) may have adverse effects including an increased risk of myocardial infarction.

Who should carry out the test?

All consumers of coffee or caffeinated beverages. Women with recurrent miscarriage who have not found a cause. Anyone who wants to take advantage of recent scientific studies to maintain good health.